Identifying neurocognitive phenotypes in autism
نویسندگان
چکیده
منابع مشابه
Identifying neurocognitive phenotypes in autism.
Autism is a complex disorder that is heterogeneous both in its phenotypic expression and its etiology. The search for genes associated with autism and the neurobiological mechanisms that underlie its behavioural symptoms has been hampered by this heterogeneity. Recent studies indicate that within autism, there may be distinct subgroups that can be defined based on differences in neurocognitive ...
متن کاملNeuroanatomical phenotypes in mental illness: identifying convergent and divergent cortical phenotypes across autism, ADHD and schizophrenia.
BACKGROUND There is evidence suggesting neuropsychiatric disorders share genomic, cognitive and clinical features. Here, we ask if autism-spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) and schizophrenia share neuroanatomical variations. METHODS First, we used measures of cortical anatomy to estimate spatial overlap of neuroanatomical variation using univariate metho...
متن کاملIdentifying Autism from Neural Representations of Social Interactions: Neurocognitive Markers of Autism
Autism is a psychiatric/neurological condition in which alterations in social interaction (among other symptoms) are diagnosed by behavioral psychiatric methods. The main goal of this study was to determine how the neural representations and meanings of social concepts (such as to insult) are altered in autism. A second goal was to determine whether these alterations can serve as neurocognitive...
متن کاملThe neurocognitive basis of autism.
The cognitive study of the underlying mental abnormalities in autism has advanced rapidly, while the biological study of the underlying brain abnormalities and of putative genetic mechanisms is lagging somewhat behind. However, the linking of cognitive and biological studies has become a real possibility. Developmental cognitive neuroscience has transformed our understanding of this enigmatic d...
متن کاملDefining language phenotypes in autism
All children with autism spectrum disorders have deficits in pragmatic aspects of communication; however, formal language abilities are extremely heterogeneous, ranging from nonverbal to superior linguistic skills. Recent studies have focused on defining different language phenotypes among verbal children. One subtype has been compared to specific language impairment (SLI), a language disorder ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
سال: 2003
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2002.1198